000			01389nam a2200253Ia 4500
003			OSt
005			20251114113646.0
008			220909b |||||||| |||| 00| 0 eng d
020			_a9789814411394
037			_cTextual
040			_aCSL _beng _cCSL
041			_aeng
084			_aE:(G116) Q4 _qCSL
245		0	_c/ edited by Edgar Jacoby _aComputational chemogenomics
260			_aSingapore : _bPan Stanford Pub., _c2014.
300			_axii, 252p. _b: ill.
500			_aIndex 243-252p.
520			_aThis book focuses on applications of compound library design and virtual screening to expand the bioactive chemical space, to target hopping of chemotypes to identify synergies within related drug discovery projects or to repurpose known drugs, to propose mechanism of action of compounds, or to identify off-target effects by cross-reactivity analysis. Both ligand-based and structure-based in silico approaches, as reviewed in this book, play important roles for all these applications. Computational chemogenomics is expected to increase the quality and productivity of drug discovery and lead to the discovery of new medicines.
650			_a Cientific requirements _9851397
650			_a Novel target ligand complexes _9851398
650			_aDrug like chemical space _9851399
700			_aJacoby, Edgar _eeditor _9851400
942			_hE:(G116) Q4 _cTEXL _2CC _n0
999			_c15831 _d15831